On the in y ivo Protein Binding of l-Hydroxy-2-acetylamino- fluorene-1-C14 in the Rat* CHARLESC. IRVINGAND ROBERTF. WILLIARD
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چکیده
At 24 hours after administration of a single dose of 3-4 mg. of l-hydroxy-2-acetylaminofluorene-1-C14 (1-hydroxy-AAF-l-C14) intraperitoneally to rats, 75 per cent of the dose had been excreted in the urine and feces. About 5 per cent of the injected radioactivity was present in the gastrointestinal contents, and only 1-2 per cent re mained in the tissues of the rat. Radioactivity equivalent to 15-19 m/mioles of 1-hydroxy-AAF-l-C14 per gm. of
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On the in y ivo Protein Binding of l-Hydroxy-2-acetylamino- fluorene-1-C14 in the Rat* CHARLESC. IRVINGAND ROBERTF. WILLIARD
At 24 hours after administration of a single dose of 3-4 mg. of l-hydroxy-2-acetylaminofluorene-1-C14 (1-hydroxy-AAF-l-C14) intraperitoneally to rats, 75 per cent of the dose had been excreted in the urine and feces. About 5 per cent of the injected radioactivity was present in the gastrointestinal contents, and only 1-2 per cent re mained in the tissues of the rat. Radioactivity equivalent to ...
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